'Key switch' found that breaks the vicious cycle of Alzheimer's…ERBB4 identified

Key points in 3 lines

1. A research team at the Institute for Basic Science has identified ERBB4, a key regulatory factor that successively worsens multiple pathologies of Alzheimer's disease, and published the findings in Nature.
2. The team led by Jung Won-seok, deputy research director, said that removing ERBB4 from model mice reduced the area and number of amyloid plaques by more than 50%.
3. The team plans to study the role of ERBB4 in other neurodegenerative brain diseases, including Parkinson's and Huntington's, to seek common therapeutic targets.

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